A mouse sperm decapacitation factor receptor is phosphatidylethanolamine-binding protein 1
نویسندگان
چکیده
منابع مشابه
Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse.
Mammalian fertilization is a multistep process that culminates in the fusion of the sperm and egg plasma membrane. It is widely accepted that the equatorial segment of the acrosome-reacted sperm is important in initiating fusion with the egg plasma membrane during fertilization. There are various proteins known to be distributed only in the equatorial segment of sperm. The role of these protein...
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The phosphatidylethanolamine (PE)-binding protein (PEBP) family is an evolutionary conserved group of proteins found in various species with multiple functions. We identified human PE-binding protein 4 (hPEBP4), a novel member of the PEBP family, as an anti-apoptotic molecule. Here we describe the cloning and functional characterization of the mouse homolog of hPEBP4 (mouse PEBP4, mPEBP4). Full...
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BACKGROUND Oocytes in humans, mice and other mammals lack identifiable centrioles. The proximal centriole brought in by the fertilizing sperm in humans and most other mammals appears to gives rise to the centrioles at the spindle poles in the zygote, and is believed to indicate that centrioles are inherited through the paternal lineage. However, both the proximal and distal sperm centrioles deg...
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The aryl hydrocarbon receptor (AhR) is a transcriptional regulator of genes involved in xenobiotic metabolism. Increasingly clear is also the role of the AhR in the control of cell growth and proliferation. By analyzing differential patterns of gene expression between wild-type (AhR+/+) and null (AhR-/-) mouse embryo fibroblasts (MEF), we have identified latent transforming growth factor-beta b...
متن کاملDecapacitation factor purification with lipid solvents.
In 1957, Chang reported the presence of a substance in the seminal plasma of several mammalian species which had the ability to reverse the capacitation process (decapacitation factor or DF). Bedford & Chang (1962) were partially able to purify DF by ultra-centrifugation. Since that time, a great deal of effort has been given to the purification, isolation and identification of this substance (...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2005
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep.1.00792